Mp1g29200.1

Protein

Length

254 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
95 - 254
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily (IPR036571)

1 50 100 150 200 254

Domains and repeats

Domain
98 - 253
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IPR003526)

1 50 100 150 200 254

Detailed signature matches

IPR036571

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily
1. SSF69765 (IpsF-like)
  
  97 - 253
  
  SUPERFAMILY
  SSF69765 (IpsF-like)
2. G3DSA:3.30.13...
  
  95 - 254
  
  GENE3D
  G3DSA:3.30.1330.50 (G3DSA:3.30.1330.50)
IPR003526

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
1. PF02542 (YgbB)
  
  98 - 251
  
  Pfam
  PF02542 (YgbB)
2. cd00554 (MECDP_synt...)
  
  99 - 251
  
  CDD
  cd00554 (MECDP_synthase)
3. MF_00107 (IspF)
  
  98 - 253
  
  HAMAP
  MF_00107 (IspF)
4. TIGR00151
  
  99 - 253
  
  TIGRFAMs
  TIGR00151 (TIGR00151)
IPR020555

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site
1. PS01350 (ISPF)
  
  132 - 147
  
  PROSITE patterns
  PS01350 (ISPF)

no IPR

Unintegrated signatures

PTHR43181 (2-C-METH...)

30 - 254

PANTHER
PTHR43181 (2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLOROPLASTIC)
PTHR43181:SF2 (2-C-...)

30 - 254

PANTHER
PTHR43181:SF2 (2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE)

Residue annotation

homotrimer interac...

99R

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

100I

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

102H

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

104F

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

106L

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

107H

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

108R

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

112N

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

147G

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

149L

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

150G

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

152P

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

153D

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

190N

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

192D

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

194T

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

201K

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

203S

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

225N

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

227K

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

228A

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

231H

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

232E

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

233K

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

246H

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

248V

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)

250L

homotrimer interaction site
99R, 100I, 102H, 104F, 106L, 107H, 108R, 112N, 147G, 149L, 150G, 152P, 153D, 190N, 192D, 194T, 201K, 203S, 225N, 227K, 228A, 231H, 232E, 233K, 246H, 248V, 250L
CDD
cd00554 (MECDP_synthase)
zinc binding site ...

105D

zinc binding site
105D, 107H, 139H
CDD
cd00554 (MECDP_synthase)

107H

zinc binding site
105D, 107H, 139H
CDD
cd00554 (MECDP_synthase)

139H

zinc binding site
105D, 107H, 139H
CDD
cd00554 (MECDP_synthase)
CDP-binding sites ...

153D

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

155G

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

197L

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

198Q

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

200P

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

201K

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

202L

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

203S

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

228A

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

229K

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

230T

CDP-binding sites
153D, 155G, 197L, 198Q, 200P, 201K, 202L, 203S, 228A, 229K, 230T
CDD
cd00554 (MECDP_synthase)

GO term prediction

Biological Process

GO:0016114 terpenoid biosynthetic process

Molecular Function

GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity

Cellular Component