Mp5g02260.1

Protein

Length

160 amino acids

Protein family membership

Mitochondria fission 1 protein (IPR016543)

Homologous superfamilies

Homologous superfamily
6 - 159
Tetratricopeptide-like helical domain superfamily (IPR011990)

1 20 40 60 80 100 120 140 160 160

Domains and repeats

Domain
19 - 133
Mitochondria fission protein Fis1, cytosolic domain (IPR033745)
Repeat
44 - 72
Fis1, N-terminal tetratricopeptide repeat (IPR028058)
84 - 134
Fis1, C-terminal tetratricopeptide repeat (IPR028061)

1 20 40 60 80 100 120 140 160 160

Detailed signature matches

IPR011990

Tetratricopeptide-like helical domain superfamily
1. G3DSA:1.25.40.10
  
  20 - 159
  
  GENE3D
  G3DSA:1.25.40.10 (G3DSA:1.25.40.10)
2. SSF48452 (TPR-like)
  
  6 - 159
  
  SUPERFAMILY
  SSF48452 (TPR-like)
IPR016543

Mitochondria fission 1 protein
1. PIRSF008835 (TPR_re...)
  
  5 - 160
  
  PIRSF
  PIRSF008835 (TPR_repeat_11_Fis1)
2. PTHR13247 (TETRATRI...)
  
  5 - 160
  
  PANTHER
  PTHR13247 (TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11)
IPR033745

Mitochondria fission protein Fis1, cytosolic domain
1. cd12212 (Fis1)
  
  19 - 133
  
  CDD
  cd12212 (Fis1)
IPR028058

Fis1, N-terminal tetratricopeptide repeat
1. PF14852 (Fis1_TPR_N)
  
  44 - 72
  
  Pfam
  PF14852 (Fis1_TPR_N)
IPR028061

Fis1, C-terminal tetratricopeptide repeat
1. PF14853 (Fis1_TPR_C)
  
  84 - 134
  
  Pfam
  PF14853 (Fis1_TPR_C)

no IPR

Unintegrated signatures

PTHR13247:SF13 (MIT...)

5 - 160

PANTHER
PTHR13247:SF13 (MITOCHONDRIAL FISSION 1 PROTEIN B)

Residue annotation

heterodimer interf...

24Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

27Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

28D

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

31R

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

43S

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

44E

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

45S

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

47M

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

48R

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

51W

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

60A

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

63Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

64R

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

66I

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

67A

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

70E

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

73L

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

76Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

78G

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

81Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

82K

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

83W

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

84E

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

86L

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

88L

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

96T

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

98D

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

101R

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

104R

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

105L

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

108Q

heterodimer interface
24Q, 27Q, 28D, 31R, 43S, 44E, 45S, 47M, 48R, 51W, 60A, 63Q, 64R, 66I, 67A, 70E, 73L, 76Q, 78G, 81Q, 82K, 83W, 84E, 86L, 88L, 96T, 98D, 101R, 104R, 105L, 108Q
CDD
cd12212 (Fis1)

GO term prediction

Biological Process

GO:0000266 mitochondrial fission

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features