Mp6g10540.2

Protein

Length

421 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
122 - 420
Pyruvate kinase-like domain superfamily (IPR040442)
Homologous superfamily
126 - 415
Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (IPR015813)

1 50 100 150 200 250 300 350 421

Domains and repeats

Domain
135 - 381
ICL/PEPM domain (IPR039556)

1 50 100 150 200 250 300 350 421

Detailed signature matches

IPR040442

Pyruvate kinase-like domain superfamily
1. G3DSA:3.20.20.60
  
  122 - 420
  
  GENE3D
  G3DSA:3.20.20.60 (G3DSA:3.20.20.60)
IPR015813

Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
1. SSF51621 (Phosphoen...)
  
  126 - 415
  
  SUPERFAMILY
  SSF51621 (Phosphoenolpyruvate/pyruvate domain)
IPR039556

ICL/PEPM domain
1. cd00377 (ICL_PEPM)
  
  135 - 381
  
  CDD
  cd00377 (ICL_PEPM)

no IPR

Unintegrated signatures

PF13714 (PEP_mutase)

136 - 381

Pfam
PF13714 (PEP_mutase)
PTHR42905 (PHOSPHOE...)

127 - 419

PANTHER
PTHR42905 (PHOSPHOENOLPYRUVATE CARBOXYLASE)
PTHR42905:SF2 (PHOS...)

127 - 419

PANTHER
PTHR42905:SF2 (PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN)

Residue annotation

tetramer interface...

137E

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

144V

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

146L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

147A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

148P

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

149A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

151F

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

152D

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

153G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

154L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

155S

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

157R

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

158L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

161Q

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

163G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

164F

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

165E

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

172F

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

176A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

177A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

181A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

182P

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

185G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

186L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

187L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

188S

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

190G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

191E

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

194D

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

195Q

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

197R

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

198L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

201Q

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

202A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

216G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

222K

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

223R

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

227G

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

230Q

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

259A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

260D

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

263T

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

266K

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

267A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

270D

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

370V

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

371A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

372M

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

374A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

375M

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

376E

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

378A

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

379L

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)

380R

tetramer interface
137E, 144V, 146L, 147A, 148P, 149A, 151F, 152D, 153G, 154L, 155S, 157R, 158L, 161Q, 163G, 164F, 165E, 172F, 176A, 177A, 181A, 182P, 185G, 186L, 187L, 188S, 190G, 191E, 194D, 195Q, 197R, 198L, 201Q, 202A, 216G, 222K, 223R, 227G, 230Q, 259A, 260D, 263T, 266K, 267A, 270D, 370V, 371A, 372M, 374A, 375M, 376E, 378A, 379L, 380R
CDD
cd00377 (ICL_PEPM)
active site cd00377

168F

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

170G

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

171G

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

172F

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

183D

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

210D

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

212D

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

239E

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

284R

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

314D

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

337N

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

339L

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)

364P

active site
168F, 170G, 171G, 172F, 183D, 210D, 212D, 239E, 284R, 314D, 337N, 339L, 364P
CDD
cd00377 (ICL_PEPM)
Mg2+/Mn2+ binding ...

183D

Mg2+/Mn2+ binding site
183D, 210D, 212D, 239E
CDD
cd00377 (ICL_PEPM)

210D

Mg2+/Mn2+ binding site
183D, 210D, 212D, 239E
CDD
cd00377 (ICL_PEPM)

212D

Mg2+/Mn2+ binding site
183D, 210D, 212D, 239E
CDD
cd00377 (ICL_PEPM)

239E

Mg2+/Mn2+ binding site
183D, 210D, 212D, 239E
CDD
cd00377 (ICL_PEPM)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

Mp6g10540.2

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component