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Control of haploid meristem activity by CLE peptide signaling in Marchantia polymorpha.

Hirakawa, Y., et al. · 2019 · PLoS Genetics   research

doi:10.1371/journal.pgen.1007997   PMID:30845139   PMC6424463

Linked genes (5)  2 core 3 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp6g07050 MpCLE1 experimental subject MpCLE1, an H-type (TDIF-like) CLE gene, was the main focus. Loss-of-function mutants showed expanded proliferative regions and enlarged gametangiophores, while overexpression reduced meristem activity. The 12-aa CLE peptide is its functional domain, restricting gametophytic meristem proliferation.
Mp1g09960 MpTDR experimental subject MpTDR, the TDIF-type receptor, mediates MpCLE1 function; knockout mutants were insensitive to MpCLE1 overexpression. MpTDR:GUS was detected in the dorsal apical meristem.
Mp5g18050 MpCLE2 sequence comparator One of two CLE genes in the genome, R-type (CLV3-like), contrasted with MpCLE1.
Mp1g27720 MpCLV1 sequence comparator A second CLE receptor encoded in the genome alongside MpTDR.
Mp3g23400 MpEF1 experimental tool Used as a constitutive promoter to drive MpCLE1 overexpression; expressed throughout the thallus.