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Independent evolution of lateral inhibition mechanisms in different lineages of land 1 plants- MpFEW RHIZOIDS1 miRNA-mediated lateral inhibition controls rhizoid cell 2 patterning in Marchantia polymorpha.

Thamm, A., et al. · 2019 · BioRxiv   research

doi:10.1016/j.cub.2020.03.032   PMID:32243863

Linked genes (4)  2 core 2 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp1g06440	MpFRH1	experimental subject	FEW RHIZOIDS1 miRNA; a repressor that inhibits MpRSL1 activity, mediating lateral inhibition to control rhizoid cell patterning. Mpfrh1 loss elevates MpRSL1 and rhizoid numbers.
Mp3g17930	MpRSL1	experimental subject	RSL class I bHLH activator of rhizoid cell fate; its mRNA is repressed by MpFRH1; gain-of-function increases rhizoids — the activator in the lateral-inhibition module.
Mp3g25140	MpAPT	experimental tool	APT (Mp...); qPCR reference.
—	MpAPT1 missing	experimental background	MpAPT1 reference gene for qPCR normalization