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JAZ is essential for ligand specificity of the COI1-JAZ co-receptor.

Monte, I., et al. · 2022 · PNAS   research

doi:10.1073/pnas.2212155119   PMID:36442090   PMC9894187

Linked genes (3)  2 core 1 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp2g26590	MpCOI1	experimental subject	Tested by pull-down/co-expression and complementation assays for ligand binding within the COI1-JAZ co-receptor. MpCOI1 binds dn-OPDA but not JA-Ile or COR, attributed to a smaller binding pocket (V377), showing it contributes to ligand specificity.
Mp6g06230	MpJAZ	experimental subject	Central subject; complementation, pull-down, and site-directed mutagenesis of its degron loop. MpJAZ specifies dn-OPDA binding regardless of COI1 origin via a unique E1/Q4 (ELPQ) degron motif, establishing that JAZ co-determines co-receptor ligand specificity.
—	MpMYC missing	citation background	Mentioned only as a conserved core signaling component (COI1-JAZ-MYC) across embryophytes; not experimentally studied here.