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DIENELACTONE HYDROLASE LIKE PROTEIN1 negatively regulates the KAI2- ligand pathway in Marchantia polymorpha.

Kameoka, H., et al. · 2023 · Current Biology   research

doi:10.1016/j.cub.2023.06.083   PMID:37480853

Linked genes (8)  4 core 4 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp5g09160 MpDLP1 missing experimental subject DIENELACTONE HYDROLASE LIKE PROTEIN1 (Mp5g09160), the focal gene; a negative regulator of the KAI2-ligand (KL) signaling pathway. Its expression is induced by the KL signal; dlp1 mutants and DLP1ox lines show altered KL-pathway output.
Mp2g11710 MpKAI2A experimental subject Putative KL (KAI2-ligand) receptor; Mpkai2a mutations introduced into dlp1/DLP1ox backgrounds to place DLP1 genetically within the KL pathway.
Mp1g02580 MpMAX2 experimental subject KL signaling gene; mutated to test its genetic relationship with DLP1 in the KL pathway.
Mp3g06310 MpSMXL experimental subject KL signaling pathway gene; mutated and analyzed as a DLP1-related KL-pathway component.
MpACTIN1 missing experimental tool qPCR reference (normalization) gene.
Mp2g04930 MpKAI2B experimental tool Marker gene for the KL signal; its expression level used as the readout to assess KL-pathway activity.
Mp6g04540 missing experimental background KL-downstream gene suppressed in Mpkai2a/Mpmax2 mutants; expression readout.
Mp1g00270 MpLOG experimental background KL-downstream gene suppressed in Mpkai2a/Mpmax2 mutants; used as a DLP1-regulated expression readout.