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The D-mannose-L-galactose pathway plays a predominant role in ascorbate biosynthesis in the liverwort Marchantia polymorpha but is not regulated by light and oxidative stress.

Ishida, T., et al. · 2024 · The Plant Journal   research

doi:10.1111/tpj.16530   PMID:37983622

Linked genes (5)  5 core 0 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp1g07760 missing experimental subject GDP-L-galactose phosphorylase (GGP/VTC2); committed step of the ascorbate pathway.
Mp2g15930 missing experimental subject Phosphomannose isomerase (PMI); enzyme of the D-mannose/L-galactose ascorbate biosynthesis pathway shown to predominate in M. polymorpha.
Mp3g15520 missing experimental subject Phosphomannomutase (PMM); D-Man/L-Gal ascorbate pathway.
Mp4g21180 MpDFR-like12 experimental subject GDP-mannose-3',5'-epimerase (GME); ascorbate pathway.
Mp6g04750 MpGMP experimental subject GDP-mannose pyrophosphorylase (GMP/VTC1); ascorbate pathway.