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Dinor-12-oxo-phytodienoic acid conjugation with amino acids inhibits its phytohormone bioactivity in Marchantia polymorpha.

Liang, W., et al. · 2024 · Plant Physiology   research

doi:10.1093/plphys/kiae610   PMID:39514772   PMC11663715

Linked genes (11)  1 core 10 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp6g07600 MpGH3A experimental subject Central gene of the study; CRISPR-Cas9 loss-of-function alleles (Mpgh3a-1ge, -2ge) were generated and shown to be unable to accumulate wound-induced dn-iso-OPDA amino-acid conjugates.
Mp2g26590 MpCOI1 experimental comparator Mpcoi1-2 mutant analyzed; wound-induced dn-OPDA-aa conjugate accumulation was only slightly diminished, indicating a minor requirement of the COI1 pathway.
Mp2g14010 MpGH3B experimental comparator Paralog contrasted with MpGH3A; not induced by OPDA and not transcriptionally regulated by dn-OPDA, so it does not contribute to conjugate formation.
MpMYCY experimental comparator Mpmycy mutant analyzed; like Mpcoi1 it showed only minor defects in dn-OPDA-aa conjugate accumulation.
Mp6g11010 MpACTIN7 experimental tool Used as the reference gene (Mp6g11010) for RT-qPCR marker gene expression analysis.
Mp5g16920 MpDIR33 experimental tool dn-OPDA-specific marker gene whose expression was measured; significantly higher in Mpgh3age plants than WT upon wounding.
Mp3g10660 MpFAD5 experimental tool Mpfad5 mutant impaired in dn-iso-OPDA biosynthesis used to show conjugates derive mainly from the canonical dn-OPDA pathway.
MpHBLH4 missing experimental tool dn-OPDA-specific marker gene co-analyzed with MpDIR; expression significantly elevated in Mpgh3age plants versus WT upon wounding.
Mp6g17330 MpDES6 citation background Cited as the Delta-6-desaturase required for hexadecatrienoic acid (16:3) biosynthesis in the hexadecanoid pathway; no experimental work here.
Mp1g20090 MpILR experimental background Sole Marchantia amidohydrolase homolog; in vitro analyses (in discussion) showed it can accept different auxin conjugates as substrates, relevant to possible conjugate hydrolysis.
Mp6g06230 MpJAZ citation background Listed only by accession (Mp6g06230); no experimental analysis reported in this paper.