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Redox buffering and H2O2 orchestrate the vegetative development of Marchantia polymorpha.

Kock C, Helmig J, Gutsche N, Dierschke T, Müller-Schüssele SJ, Zachgo S. · 2025 · The Plant journal : for cell and molecular biology   research

doi:10.1111/tpj.70317   PMID:40680301   PMC12274077

Linked genes (6)  2 core 4 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp5g18050 MpCLE2 experimental subject Exogenous application of the MpCLE2 peptide (MpCLE2p) expanded the meristem/stem cell zone and altered redox dynamics, linking MpCLE2 signaling to H2O2/redox-dependent control of cell proliferation.
Mp1g07310 MpGSH1 missing experimental subject Knockdown lines of MpGSH1, the sole gamma-glutamylcysteine synthetase gene, were generated by artificial miRNA. Reduced GSH levels impaired meristem development, showing MpGSH1-dependent glutathione redox buffering is essential for vegetative growth and meristem maintenance.
Mp7g01530 MpTCP1 missing citation comparator Cited as a redox-related bHLH transcription factor whose mutants show elevated H2O2, supporting the role of ROS in M. polymorpha growth.
MpEF1a missing experimental tool The MpEF1alpha promoter was used to drive constitutive expression of the roGFP2-hGrx1 redox sensor in transgenic lines.
Mp1g26670 MpMIR160 experimental tool The MpMIR160 precursor served as the artificial microRNA scaffold for constructing the MpGSH1 knockdown vector.
MpPLT missing citation background Cited transcription factor mentioned in the context of redox-dependent growth control.