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The cytochrome P450 enzyme MpCYP78E1 inhibits meristem initiation and activity in Marchantia polymorpha.

Spencer V, Casey C, Mosiolek M, Jandrasits K, Edelbacher N, Dolan L. · 2025 · Current biology : CB   research

doi:10.1016/j.cub.2025.06.071   PMID:40712584

Linked genes (3)  2 core 1 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp1g14150	MpCYP78-like1	experimental subject	Cytochrome P450 (Mp1g14150); gain-of-function (MpCYP78E1GOF) and CRISPR lines show MpCYP78E1 inhibits meristem initiation and activity, acting as a brake on dichotomous branching; expression correlates inversely with meristem activity.
Mp3g25440	MpPR10.2	experimental subject	MLP-LIKE PROTEIN 423 (Mp3g25440); CRISPR-targeted (gRNA1/2) and identified among genes up-regulated during meristem inactivation, studied alongside MpCYP78E1.
Mp1g10020	MpSPL1	citation background	SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 1; cited as a meristem regulator whose activity is maintained by apically produced auxin.