MarpolBase - Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants.

Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants.

Yadav R, Liu G, Rana P, Pullagurla NJ, Qiu D, Jessen HJ, Laha D. · 2025 · PLoS genetics research

Gene ID	Name	Evidence / Role	Function (this paper)
—	MpHSFB1 missing	experimental subject	Heat shock transcription factor shown by Y2H/BiFC to physically interact with MpIPMK; EMSA showed MpHSFB1 binds the HSE element and MpIPMK potentiates its DNA-binding activity in a dose-dependent manner.
Mp1g22660	MpIPMK	experimental subject	The single IPK2/IPMK homologue in M. polymorpha. CRISPR-Cas9 Mpipmk knockouts showed reduced 4/6-InsP7 levels and impaired heat-stress acclimation/thermomorphogenesis; ectopic MpIPMK rescued yeast ipk2Δ defects and heat-induced hypocotyl phenotypes, showing IPK2 function is conserved across land plants.
—	MpACT7 missing	experimental tool	Used as the internal reference gene for qRT-PCR normalization.