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Spatial metabolomics as a new avenue in plant developmental biology: insights into serine biosynthesis during spermatogenesis in Marchantia polymorpha.

Tabeta H, Uzaki M, Hirai MY. · 2025 · Plant signaling & behavior   research

doi:10.1080/15592324.2025.2571669   PMID:41104778   PMC12536615

Linked genes (1)  1 core 0 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp8g16970 MpPGDH missing experimental subject Encodes 3-phosphoglycerate dehydrogenase, the key enzyme of the phosphorylated serine biosynthesis pathway. The Mppgdh knockout mutant, defective in sperm formation, was analyzed by spatial metabolomics, revealing local serine depletion in antheridial receptacles (cell-autonomous serine regulation) that whole-organ analysis had missed. MpPGDH is expressed in the middle area of antheridial receptacles.