MarpolBase - Mechanistic Insights into d-Alanine-Induced Plant Growth Inhibition: Synergistic Roles of Transport, Transcriptional Regulation, and Metabolic Perturbations.

Mechanistic Insights into d-Alanine-Induced Plant Growth Inhibition: Synergistic Roles of Transport, Transcriptional Regulation, and Metabolic Perturbations.

Chen H, Zhang Y, Shi Y, Zeng S, Chen K, Mou W, Li D. · 2025 · Journal of agricultural and food chemistry research

Gene ID	Name	Evidence / Role	Function (this paper)
—	MpalphaCAL missing	experimental subject	Expression of the alpha carbonic anhydrase-like subfamily (MpalphaCALs) in M. polymorpha is altered by ectopic AtACO4 expression, linking carbonic anhydrase regulation to enhanced d-Ala growth inhibition.
Mp2g07170	MpBZIP4	experimental subject	Transcriptomics identified MpBZIP4 as a d-Ala-responsive bZIP transcription factor that negatively regulates d-alanine tolerance in M. polymorpha.
—	MpDAT missing	experimental subject	MpDAT, a transaminase, is shown to partially metabolize the imported d-alanine in M. polymorpha, contributing to d-Ala turnover.
Mp6g02000	MpLHT1 missing	experimental subject	The authors show that d-alanine is transported into Marchantia polymorpha cells via the lysine-histidine transporter MpLHT1, identifying it as the route of d-Ala uptake driving growth inhibition.