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Salicylic acid and the unique TGA transcription factor controls plant immunity against Pseudomonas syringae in Marchantia polymorpha.

Michavila S, Espinosa-Cores L, Kneeshaw S, Torres S, Siroka J, Zamarreno AM, Gonzalez-Zuloaga M, Garcia-Mina JM, Novak O, Solano R, Gimenez-Ibanez S. · 2026 · Plant & cell physiology   research

doi:10.1093/pcp/pcaf164   PMID:41351870   PMC13078155

Linked genes (31)  2 core 29 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp3g14110 MpPR1 experimental subject Identified in this paper's transcriptome as an SA- and MpTGA-coregulated gene, consistent with its known SA responsiveness, serving as a readout of the SA/MpTGA immune output.
Mp2g13330 MpTGA experimental subject The single Marchantia TGA TF, encoded by Mp2g13330. CRISPR Mptga mutants (Mptga-7ge, Mptga-8ge) showed enhanced susceptibility (greater symptoms, higher bacterial titres) to Pseudomonas syringae, while MpTGA overexpressors (MpTGA-2ox) remained asymptomatic, showing MpTGA is essential for SA-dependent resistance.
Mp3g23400 MpEF1 experimental tool Housekeeping gene used as the internal control for qRT-PCR normalization; its promoter (proMpEF1a) also drove the NahG transgene.
Mp1g27170 MpACRE132 experimental background Rapidly responsive defense gene detected in this paper's transcriptome.
MpbHLH missing experimental background bHLH transcription factor genes upregulated in the transcriptome.
MpbZIP missing experimental background bZIP transcription factor genes upregulated in the transcriptome.
Mp6g18000 MpCML42 experimental background Calmodulin-like (CML42) defense gene detected in the transcriptome.
MpEDS5A missing citation background Single EDS5-related gene, cited in the context of SA pathway/complementation in Arabidopsis.
MpERF missing experimental background ERF transcription factor genes upregulated in the transcriptome.
MpGST missing experimental background Glutathione S-transferase genes upregulated in the immune/SA transcriptome.
Mp2g20660 MpICS citation background Single isochorismate synthase gene, cited regarding limited homology to AtICS1 and SA-biosynthesis limitations.
MpMYB missing experimental background MYB transcription factor genes upregulated in the transcriptome.
MpNAC missing experimental background NAC transcription factor genes upregulated in the transcriptome.
MpNLR missing experimental background NLR-class immune receptor genes upregulated in the transcriptome.
Mp1g02380 MpNPR citation background Single Marchantia NPR ortholog, cited from prior work as not a master SA regulator.
MpPLATZ missing experimental background PLATZ transcription factor genes upregulated in the transcriptome.
MpPOD missing experimental background Class III peroxidase (POD) gene family responsive in the transcriptome (190 members in the genome).
MpPR11 missing experimental background Chitinase PR genes upregulated in the transcriptome.
MpPR15 missing experimental background Cupin-type PR15/16 genes upregulated in the infection/SA transcriptome (Mp5g00920, Mp5g00990, Mp5g01080, Mp5g01070).
MpPR16 missing experimental background Cupin-type PR15/16 genes upregulated in the infection/SA transcriptome.
MpPR2 missing experimental background Beta-1,3-glucanase PR genes upregulated in the infection/SA transcriptome.
MpPR3 missing experimental background Chitinase PR genes upregulated in this paper's transcriptome.
Mp2g21910 MpPR4 experimental background Barwin-like chitinase PR genes upregulated in the transcriptome.
Mp6g06310 MpPR5 missing experimental background Thaumatin-like PR5 gene upregulated in the infection/SA transcriptome.
MpPR6 missing experimental background Protease-inhibitor PR genes upregulated in the transcriptome.
MpPR7 missing experimental background Protease PR genes upregulated in the transcriptome.
MpPR8 missing experimental background Chitinase PR genes upregulated in the transcriptome.
MpPR9 missing experimental background Class III peroxidase PR genes upregulated in the transcriptome.
MpRLK missing experimental background Receptor-like kinase genes upregulated in the immune/SA transcriptome.
MpROXY missing citation background CC-type glutaredoxins (ROXYs), cited as MpTGA redox-regulatory interactors.
MpWRKY missing experimental background WRKY transcription factor genes upregulated in the immune/SA transcriptome.