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Initiation of asexual reproduction by the AP2/ERF gene GEMMIFER in Marchantia polymorpha.

Takahashi G, Yamaya S, Romani F, Bonter I, Ishizaki K, Shimamura M, Kiyosue T, Haseloff J, Hirakawa Y. · 2026 · Current biology : CB   research

doi:10.1016/j.cub.2026.03.083   PMID:42086024

Linked genes (5)  3 core 2 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp5g18050 MpCLE2 experimental subject CLAVATA3/ESR-related 2 peptide; MpCLE2 signaling negatively regulates gemma-cup formation.
Mp6g04830 MpGCAM1 experimental subject GEMMA CUP-ASSOCIATED MYB1; its expression in early gemma development is promoted downstream of MpGMFR.
Mp4g00380 MpGMFR experimental subject GEMMIFER, an AP2/ERF (class VIII) family gene (= MpERF14, Mp4g00380); identified as a key regulator that initiates asexual reproduction (gemma/gemma-cup formation) in M. polymorpha.
Mp1g20040 MpERF1 experimental comparator One of three class VIII AP2/ERF genes (Mp1g20040); its coding sequence was introduced in comparison experiments.
Mp5g06970 MpERF20 experimental comparator LOW-AUXIN RESPONSIVE (LAXR) AP2/ERF (Mp5g06970), a class VIII paralog of MpGMFR; CDS introduced for comparison.