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Replicated repurposing of an ancestral transcriptional complex in land plants.

Kongsted TE, Romani F, Airoldi CA, Haseloff J, Glover BJ. · 2026 · Current biology : CB   research

doi:10.1016/j.cub.2026.04.031   PMID:42105757

Linked genes (8)  5 core 3 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp2g05070 MpBHLH12 experimental subject bHLH component of the MBW complex; MpbHLH12 interacts with the TTG1-like WDR proteins.
Mp3g07510 MpMYB02 experimental subject Orthologous MYB acting with MpMYB14 in the MBW transcriptional complex controlling flavonoid pigmentation and epidermal traits.
MpMYB14 missing experimental subject R2R3-MYB controlling flavonoid/anthocyanin (auronidin) pigmentation; one of two orthologous MYBs (with MpMYB02) in the repurposed MBW (MYB-bHLH-WD40) complex.
Mp5g03900 MpWDR1 experimental subject TTG1-like WD40-repeat protein; MpWDR1 (or MpWDR2) complements flavonoid-pigmentation and epidermal defects, defining the WDR component of the MBW complex.
Mp5g01830 MpWDR2 experimental subject TTG1-like WD40-repeat protein functionally redundant with MpWDR1 in complementing MBW-complex defects.
Mp5g06230 MpWDR3 experimental comparator Third TTG1-like WDR that, unlike MpWDR1/MpWDR2, does NOT complement the defects.
Mp2g04270 MpCDKA experimental tool Cyclin-dependent kinase A; interaction partner of MpCYCD;1 used as a BiFC positive control.
Mp8g17230 MpCYCD_1 experimental tool Cyclin used (MpCYCD;1-nYFP with MpCDKA-cYFP) as a positive control for the BiFC interaction method.