MarpolBase - Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator.

Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator.

Raval PK, Thaler NK, Mitchell C, Lozano-Quiles M, Kajander T, Djamriani DW, Reiners J, Smits SH, Butcher SJ, Battersby BJ, Gould SB. · 2026 · bioRxiv : the preprint server for biology research

doi:10.64898/2026.05.28.728419 PMID:42282756 PMC13252137

Linked genes (1) 1 core 0 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
—	MpTACO1 missing	experimental subject	The Marchantia polymorpha TACO1 (YebC/TACO1 family translation activator). The authors demonstrate it is dually targeted to mitochondria and plastids, resolve its structure at 2.34 A by X-ray crystallography, and model it fitting into the chlororibosome peptidyl transfer centre, supporting a conserved role as a translation enhancer of polyproline-motif proteins.