| Database | ID | Description |
|---|---|---|
| ProSiteProfiles | PS50011 | Protein kinase domain profile. |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) |
| Pfam | PF00069 | Protein kinase domain |
| CDD | cd07858 | STKc_TEY_MAPK |
| FunFam | G3DSA:1.10.510.10:FF:000013 | Mitogen-activated protein kinase |
| ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. |
| ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. |
| Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 |
| ProSitePatterns | PS01351 | MAP kinase signature. |
| SMART | SM00220 | serkin_6 |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 |
| FunFam | G3DSA:3.30.200.20:FF:000046 | Mitogen-activated protein kinase |
| PANTHER | PTHR24055 | MITOGEN-ACTIVATED PROTEIN KINASE |
| KEGG | K04371 | mitogen-activated protein kinase 1/3 [EC:2.7.11.24] |
| KOG | KOG0660 | Mitogen-activated protein kinase; [T] |
| MapolyID | Mapoly0015s0179 | - |
| GO | GO:0005634 | nucleus |
| GO | GO:0005524 | ATP binding |
| GO | GO:0035556 | intracellular signal transduction |
| GO | GO:0004707 | MAP kinase activity |
| GO | GO:0004672 | protein kinase activity |
| GO | GO:0004674 | protein serine/threonine kinase activity |
| GO | GO:0006468 | protein phosphorylation |
| GO | GO:0005737 | cytoplasm |
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpMPK1 | Mitogen-activated protein kinase | Published |
Essential MAPK gene (knockouts unobtainable by gene targeting) studied via conditional knockout; CRISPR alone gave only mosaic mutants while co-transformation with cDNA complementation vectors yielded monoclonal frameshift mutants. Heat-shock/dexamethasone-induced Cre/loxP excision of the rescuing cDNA caused severe growth defects, confirming a critical role in growth and development.
1 core 1 peripheral
Sequences: |
Gene UTR + CDS + intron |
| >Mp2g08950.1 GTAGTGGTCG AACGCACCCT TGCAGCAGCA GGAGGATAGA CACGGAGGCG AGCGAGGGAG AGGGTCGGGA GGGGAGTGAC GAGAGTCGAC GACATGCAGC AGGAAATTTG GCGTGCGAAT AGAAGGAGCT GAGAAAGGGA GAGCGGGAGG TAGACAGCAG ACATCGCACG TCCTGGGCTG AAGAAAACGG AGAGGAAGAA GGCGCAAGAA GTTTCATTTC GACAGACGGA GCGAGGGAGG GATTAAAGGG AGCGAGTGAG TGAGCGGGCG AGGAGTGAGA GTGCGAGTTC TGCGTTTCGT TTTCGTGTTT ATTGGGATTT GGGGGAGTGG AGGGAGGGGA ATCGAGCGGA CGGCTGGTGG TGGATTAGTT CTCTGTGTTG TAGACCCAAA GGTGTTGCTG AGGCAGGCAG GGCAGAGGAA GAGGAGGAGG AAGAGGAAGA GAGAGAATGG GGGAGGGCGA GCAGATCGGG AAGTGAAGTT CTTAGTGGAG GCCAAGAGCG AGCGAGGGTG GATAAAAGAT ATAGGGAGGT GAGGACGCCG ATGCAGGAGA CCCCATGGAT TCCGCAGCAG CTGCCGCAGC CGCGGAGGGC AACATAGCAG GTGTTCCAAC GCACGGTGGG CAATACACTC TCTACAACAT CTTCGGCAAC TTGTTCGAGG TTTCTGCCAA ATACGTGCCT CCGATTCGTC CCATCGGTAG AGGGGCCTAC GGCATTGTCT GGTACGCTTC TGCCTTTGTA TCAGTTTAGA TTCAACGCTT TACCGTTTGC TAGCGCTTTC TAATCCTGCC ACTCGCCCGG TCGGCTCGAG GCCTGGTTCG TCCAATCATT CGGAGCTTTC CATCTTCCTT CAACTCTTGG TGTTTTCTAT TTTCTCTTCA TGGCAGGAGG CTTTTCGATG ATTGTACTGG CCGATCCCGT CTTGATGGGA ACTCGGAGAA AGGGAGTGGT TCACATGTGA TAGCTTAGCG TCGTGGACTG AGGCGAGGGG TTACTATGGT TATTGGTTAC TTGGTCTATG GTTACTTGGA CCTTTGTCGG TGCCATTTAA GTCCATGTTT CTTGCTGACT TCACATGCAT GGCCTCTACT TTGGATAAAT TGGACGAGTT GTGAACATAA ACATAATCTG TTCTTATTGG ACCTACAAGG TTTCCATTGA GATATCTCAG TCGGATGGTT TCTTTGAACG ATCAGATATT GTAACCTCAG AACCCTTCTA GGAGCTGTTT TTCTTTAATT CAGGAGTGCT CATCTTCATC ACCTTTGTTT CCTCATGAAT TGATCATCTA TATTGGACTA GTCATGCATA TATAGGAATT GTTTCATGGT CAAGACTCAC GTTGCCAAGT TATTCATTTT CGAAAGCCTG TAGGTTCAAC TTTTGGATGT AGACATGATA TTTAAAGTTT ATTCCTTGTT ACTGAGCTAC ACTTGCATGT GCATTACATA AATCACCGTC GCCATGACAG CTTATTCTCG TGATTCTTAT ATGCCTTGTA AGACTTCATA AATGAGAGAG ATTGTCAGAT CCTAAAGTAA TTCTTCCGTG TCCCTGATGT CTCGTCTTGT CTTGATTAGC CAAAAGAGCA AAAGTTTTTT TTTTCAAGTT TCATATGTGA AAATGACCAG CACTATCCTA GATCATGTTT GTTAGTCTGT GTGTATTAAT TAGCCAGGAT AGCAAAAGAG CTTTTTGTGT GACTCTCATT TATTCAATGT TTCAATCACT ATCTTAGAGC ATATGTGTCT TCCTGTGCTT CTTACACAAT CCTCTTGGCA TGTTCATATA GCTGGTAGAT TATAATTTGG CTCTGTCGTG TCACTTTAGC TGTAGTGTTT CTAGCGTTTT TGTAGATCTG CGTTGTAGAC AGGTTGACAC CACCTCTTGA TCTAATTGGC AAGTTTTGTG GAGGTTGGTA GATTAACCTC ACTATGAGCC ATGATAATTC TTACTTTGTC GTGTAGAGAT GGTTCTCTGT CACCGTTTTC CAGCTGAAAT TGTTATCGCT TTAGACCTTT GTCGTAGAAA GTCTAGCACA ATAAGCGACT TGATATCATT TTCAGTTTGT TATCTGTGAT ATTTTCAGTT CTTCGTACAA GGATTCATGC AAGGTACATC TAACTTCAAC AGGGTTTCAC ATTGCGATTT ACGGTTTGAA GTGGCGTTTC ATTTTTCAAC CCGGAACACA CACATTGGAT CTTAGTCAGA GATAGTTACA ATTTCACAAT ATCTTCAATT TCAAGAACAT GAGGTCCTCT CAATCTAATA TAAAATTCAT AAATTTGTAT TAATGAGATT TACACTTTTG ATCATATTAT AAGATTGACG TTCACGATCA TCTCCATTTG TCACGCATGC AAGATTGAGT TCGTTGCAAA TTCAGTATTC TTAGTTCAAA CTTTTGCTGG ATTGGAATGG TAGGAGAAGG TAGGCCAATC ATCAGCACTG TAGATTGTAT GTCAAGTACC GCTCTTTCAT AGTAGTTCCA TGAGACATGG GCACACAAAG TTTTGAACAT AGGATAAAGC ACACTTGTTG GTCATTTATG AAGAAAGAAG ATACGATGTT GTCTAAACAC TGAAAGGGTA GAATGGCATT ACTCTTGACA TTTTGCGCAA CTCACACCAA GGATTTCTCC GGAGAAGTTG TGTGTTGTTA TGAGGAGAAG CTGTAGGCAG GTAATGTAGA GTCCAGGTTT CGTTCTGAGG ATCAGTTTCT TGGTGTGGCC TTCACAACTT TCACTGAATG TGGTATCCAT ACTCGTGGAA ATCGTTCTGG CACTATCTAA TTTTGGACTA GCTGTGTATG TACTGTTCAG ACATGTACTG ACGTAATGCA CTTTTTGATG ACTAACAACT TATGGATCAT TTGTGTGTGT GTTAGTTCTG CTGTCAACTC CGAGACAACC GAGGAAGTTG CAATAAAAAA GATCGGAAAT GCCTTCGACA ATAGAATTGA CGCCAAGCGT ACTCTTCGTG AGATCAAACT TCTTCGACAC ATGGACCACG AAAATGTAAA GCTTCTGTCA TATATTTCAT GATATGTAAC AAATCAAGTC GAATATGATA TGGTCTGCCT CTCTTGTTCT GCTATGCTGC ATGTATGTTT TCATCGACTA CCGGTGTGTT TGCAATAGAG TCATACATTT GCCAAAAGGA AGATAACCGA CCCCTCTCAC GATGTTTGTG ATAATGCTTT TCGTGGGATA GCTAGCGAAT GATATGTTCA ATCTTGTGAC TTCAGCAGAT GACCAGAGTT TGTCTTTGAC TGCAAGGTCT GTTTCTCAAT TTTTGCCCCA TCGGACATCT TGTTTACGAA TGACATGTAA TCTTACAGGT AGTCGCCATT AGAGACATCA TTCGTCCTCC TACTAGAGAT GAATTCAACG ATGTCTACAT CGTCTATGAA CTCATGGATA CGGATTTGCA CCAGATCATC CGCTCCAATC AACCTCTTAC GGAAGATCAT TGTCAGGTCT GATCTTGACC AAGGCTCTGT AGTCGGCGCC GGTTAAAAAT TGTTTTTCTT TATGGCTGAT CGGTGTAGTG TCATCAAGCA GTTTTCTCAT ATGGTTTTCA TCTGAAAATG AACGCAATAT GCATTATATA GTGGATTGCT GGTCAAATTT TGTAGGCAAA TATATACGAG GATGTAGTTT GGACTGCAGT CAAAATCAAA AAAGGGTTTT GAAATGTAGC CTTCCTCACA TCTGTTATCA AGATTAACTG ATGGTGCTCG TGCACTCAAG TTGGATCATT TCTCAGCTAG GTAGCTGATT CATCTGCTAA TACCTTATGT GGGATGCCGC AACATGTTGT GCAACAGTAC TTCCTGTACC AGTTGTTACG AGGTTTGAAG TATATTCACT CTGCCAACGT TCTCCATCGT GACCTGAAAC CGAGCAACTT GCTACTCAAC GCGAATTGTG ATTTGAAGAT CTGTGATTTT GGGTTGGCAA GGACCACGTC GGAGACCGAC TTCATGACCG AGTATGTCGT TACCCGATGG TATCGAGCTC CGGAACTGTT ATTGAATTGT AACGAGTATA CTGCCGCCAT CGACGTGTGG TCTGTAGGAT GTATATTCAT GGAGTTGTTG AATCGAGAAC CTCTTTTTCC TGGAAGAGAT TACGTTCAGC AACTAAAACT GATCACTGAG GTAAGATTCA TAGATTAATT TGGCTTGTAC TGTAGTGACG ATCAGTGTGT GTTCCTTGGT AAGGTGGTCG GGTCTCAACA AAAATTGCGC TGAGTACAAG AGCGGACCAC TTCTGTCGTT TACTCCACCT GTACAAGCGT TACCTTCACG GCTGCCTTTT GCTAGCCTCT TTCTGGTTAG CCTCTCCTTT CTTATGGAGT TCGTAGACTG AAGTGCAGCT TGTGGCAATT CAATTCTGAC TTGGAGTAGT AATGATGTTT CTTCAGCTCA TAGGATCCCC AGAGGACTCT GACCTCGGGT TTCTGAAAAG TGAGAATGCC AAGCGCTACA TGCAACAGCT CATGAGATAT CCGAAGCAAC CTTTGGGAAG AAAGTATCCC AACATGAATC CTGCCGCCGT CGACCTTATA GAGAGGATGC TGGTCTTCGA CCCCTACAAA CGTATCACAG GTCAGTTGAC ACAAAGATTA CCACGTTTTG TTCTGAAGAG CAATATTCTC ATCGAAGTTG GTTTTTGATT TTTCCTCTTG GTCATATCCT TCGACCTTTC TCGTAGGTAT AGGCTCCTAG TGAATTGAAT GTTTCTTTCC TGTACCGTGG GTTTTTATTA ACTTTTTCTT CGTCCGTTGT ATTATGCTGG GTCCTTGCAG TGGAGCAGGC ATTGAGTCAT CCTTATCTGG CTAGCCTGCA TGATATCAAC GACGAGCCGG CCTGCCACGC CCCTTTTGAG TTTGATTTTG AGCAGCCCTC GTTTACTGAG GAACACATTA AGGAGCTGAT TATGATGGAA GCTCTTGCGT TCAATCCCCT ACCAGACATG ATGCAATAGA AACCAGATAC GGGTCGGTGA TCTTTAGTTC TTCCATCGCT CAGGCAGTTT GAGAAGGATT TCCCTGTGGT GTTGCGAGTT GGAGATTTCC TCAATTGTGC AGATCTCTTG TAAGTCATTG TGGTTGTTTA AAAAATTAAA ACGGTGATTG ACATTTGGAA TACCGATGTA GAAAATCTCC TGACACTCGT CAGTCAAAGA TAATTTTTTA TGGCTCTGGC CGTGACATTG CTTTGTGGTA TATCTCATAC GGAAATAGTA CTCGTGTTCC ACTACTTGCG TTCCCTGCCA GCCACTCAAA TCAGCCCATT TATCAGCAAC CATTCCCTGG CTCCTTCTCT TCCAAGTAGC TGCCCTTGTC CCCTGATGTG AGTGTGTGAG ATTGTACTTC TAGAGCAGTG CCAACTCAAA CCGTACGACG TAGTTTAAGA GTTTGGGAGA GTGATGGGTG TGGAATGGTA CGCATAAAGC ACTGCCGGTC ATAACCGTTC TCAGGTTGCT ACCAAGTAGA GTTGAACTCA GGAACACCCG TCTACTTGAG TGGTTCCATC CAACTTAGAG AGATCGTATT CATGTAGTAT CTTCTGCCAT AGCTTTTCAG TCAGAGAGAC AGAGGGAGAG GGATAGAGTC CTCCATGAGG GACTGTATGT GGAGTGGGTG TTTGACAAAC ACTAATATGA TGATCTGCAG CTAGTGTGTA CTTTAGTTTG TTGCCAACTG CTTTGGCTCT GTACTGATTC TAAATAAAAG TCTTGCCTTT TATCGAGGGC GGGTGGGCAA ATCAATTAC |
mRNA UTR + CDS |
| >Mp2g08950.1 GTAGTGGTCG AACGCACCCT TGCAGCAGCA GGAGGATAGA CACGGAGGCG AGCGAGGGAG AGGGTCGGGA GGGGAGTGAC GAGAGTCGAC GACATGCAGC AGGAAATTTG GCGTGCGAAT AGAAGGAGCT GAGAAAGGGA GAGCGGGAGG TAGACAGCAG ACATCGCACG TCCTGGGCTG AAGAAAACGG AGAGGAAGAA GGCGCAAGAA GTTTCATTTC GACAGACGGA GCGAGGGAGG GATTAAAGGG AGCGAGTGAG TGAGCGGGCG AGGAGTGAGA GTGCGAGTTC TGCGTTTCGT TTTCGTGTTT ATTGGGATTT GGGGGAGTGG AGGGAGGGGA ATCGAGCGGA CGGCTGGTGG TGGATTAGTT CTCTGTGTTG TAGACCCAAA GGTGTTGCTG AGGCAGGCAG GGCAGAGGAA GAGGAGGAGG AAGAGGAAGA GAGAGAATGG GGGAGGGCGA GCAGATCGGG AAGTGAAGTT CTTAGTGGAG GCCAAGAGCG AGCGAGGGTG GATAAAAGAT ATAGGGAGGT GAGGACGCCG ATGCAGGAGA CCCCATGGAT TCCGCAGCAG CTGCCGCAGC CGCGGAGGGC AACATAGCAG GTGTTCCAAC GCACGGTGGG CAATACACTC TCTACAACAT CTTCGGCAAC TTGTTCGAGG TTTCTGCCAA ATACGTGCCT CCGATTCGTC CCATCGGTAG AGGGGCCTAC GGCATTGTCT GTTCTGCTGT CAACTCCGAG ACAACCGAGG AAGTTGCAAT AAAAAAGATC GGAAATGCCT TCGACAATAG AATTGACGCC AAGCGTACTC TTCGTGAGAT CAAACTTCTT CGACACATGG ACCACGAAAA TGTAGTCGCC ATTAGAGACA TCATTCGTCC TCCTACTAGA GATGAATTCA ACGATGTCTA CATCGTCTAT GAACTCATGG ATACGGATTT GCACCAGATC ATCCGCTCCA ATCAACCTCT TACGGAAGAT CATTGTCAGT ACTTCCTGTA CCAGTTGTTA CGAGGTTTGA AGTATATTCA CTCTGCCAAC GTTCTCCATC GTGACCTGAA ACCGAGCAAC TTGCTACTCA ACGCGAATTG TGATTTGAAG ATCTGTGATT TTGGGTTGGC AAGGACCACG TCGGAGACCG ACTTCATGAC CGAGTATGTC GTTACCCGAT GGTATCGAGC TCCGGAACTG TTATTGAATT GTAACGAGTA TACTGCCGCC ATCGACGTGT GGTCTGTAGG ATGTATATTC ATGGAGTTGT TGAATCGAGA ACCTCTTTTT CCTGGAAGAG ATTACGTTCA GCAACTAAAA CTGATCACTG AGCTCATAGG ATCCCCAGAG GACTCTGACC TCGGGTTTCT GAAAAGTGAG AATGCCAAGC GCTACATGCA ACAGCTCATG AGATATCCGA AGCAACCTTT GGGAAGAAAG TATCCCAACA TGAATCCTGC CGCCGTCGAC CTTATAGAGA GGATGCTGGT CTTCGACCCC TACAAACGTA TCACAGTGGA GCAGGCATTG AGTCATCCTT ATCTGGCTAG CCTGCATGAT ATCAACGACG AGCCGGCCTG CCACGCCCCT TTTGAGTTTG ATTTTGAGCA GCCCTCGTTT ACTGAGGAAC ACATTAAGGA GCTGATTATG ATGGAAGCTC TTGCGTTCAA TCCCCTACCA GACATGATGC AATAGAAACC AGATACGGGT CGGTGATCTT TAGTTCTTCC ATCGCTCAGG CAGTTTGAGA AGGATTTCCC TGTGGTGTTG CGAGTTGGAG ATTTCCTCAA TTGTGCAGAT CTCTTGTAAG TCATTGTGGT TGTTTAAAAA ATTAAAACGG TGATTGACAT TTGGAATACC GATGTAGAAA ATCTCCTGAC ACTCGTCAGT CAAAGATAAT TTTTTATGGC TCTGGCCGTG ACATTGCTTT GTGGTATATC TCATACGGAA ATAGTACTCG TGTTCCACTA CTTGCGTTCC CTGCCAGCCA CTCAAATCAG CCCATTTATC AGCAACCATT CCCTGGCTCC TTCTCTTCCA AGTAGCTGCC CTTGTCCCCT GATGTGAGTG TGTGAGATTG TACTTCTAGA GCAGTGCCAA CTCAAACCGT ACGACGTAGT TTAAGAGTTT GGGAGAGTGA TGGGTGTGGA ATGGTACGCA TAAAGCACTG CCGGTCATAA CCGTTCTCAG GTTGCTACCA AGTAGAGTTG AACTCAGGAA CACCCGTCTA CTTGAGTGGT TCCATCCAAC TTAGAGAGAT CGTATTCATG TAGTATCTTC TGCCATAGCT TTTCAGTCAG AGAGACAGAG GGAGAGGGAT AGAGTCCTCC ATGAGGGACT GTATGTGGAG TGGGTGTTTG ACAAACACTA ATATGATGAT CTGCAGCTAG TGTGTACTTT AGTTTGTTGC CAACTGCTTT GGCTCTGTAC TGATTCTAAA TAAAAGTCTT GCCTTTTATC GAGGGCGGGT GGGCAAATCA ATTAC |
CDS |
| >Mp2g08950.1 ATGGATTCCG CAGCAGCTGC CGCAGCCGCG GAGGGCAACA TAGCAGGTGT TCCAACGCAC GGTGGGCAAT ACACTCTCTA CAACATCTTC GGCAACTTGT TCGAGGTTTC TGCCAAATAC GTGCCTCCGA TTCGTCCCAT CGGTAGAGGG GCCTACGGCA TTGTCTGTTC TGCTGTCAAC TCCGAGACAA CCGAGGAAGT TGCAATAAAA AAGATCGGAA ATGCCTTCGA CAATAGAATT GACGCCAAGC GTACTCTTCG TGAGATCAAA CTTCTTCGAC ACATGGACCA CGAAAATGTA GTCGCCATTA GAGACATCAT TCGTCCTCCT ACTAGAGATG AATTCAACGA TGTCTACATC GTCTATGAAC TCATGGATAC GGATTTGCAC CAGATCATCC GCTCCAATCA ACCTCTTACG GAAGATCATT GTCAGTACTT CCTGTACCAG TTGTTACGAG GTTTGAAGTA TATTCACTCT GCCAACGTTC TCCATCGTGA CCTGAAACCG AGCAACTTGC TACTCAACGC GAATTGTGAT TTGAAGATCT GTGATTTTGG GTTGGCAAGG ACCACGTCGG AGACCGACTT CATGACCGAG TATGTCGTTA CCCGATGGTA TCGAGCTCCG GAACTGTTAT TGAATTGTAA CGAGTATACT GCCGCCATCG ACGTGTGGTC TGTAGGATGT ATATTCATGG AGTTGTTGAA TCGAGAACCT CTTTTTCCTG GAAGAGATTA CGTTCAGCAA CTAAAACTGA TCACTGAGCT CATAGGATCC CCAGAGGACT CTGACCTCGG GTTTCTGAAA AGTGAGAATG CCAAGCGCTA CATGCAACAG CTCATGAGAT ATCCGAAGCA ACCTTTGGGA AGAAAGTATC CCAACATGAA TCCTGCCGCC GTCGACCTTA TAGAGAGGAT GCTGGTCTTC GACCCCTACA AACGTATCAC AGTGGAGCAG GCATTGAGTC ATCCTTATCT GGCTAGCCTG CATGATATCA ACGACGAGCC GGCCTGCCAC GCCCCTTTTG AGTTTGATTT TGAGCAGCCC TCGTTTACTG AGGAACACAT TAAGGAGCTG ATTATGATGG AAGCTCTTGC GTTCAATCCC CTACCAGACA TGATGCAATA G |
Protein |
| >Mp2g08950.1 MDSAAAAAAA EGNIAGVPTH GGQYTLYNIF GNLFEVSAKY VPPIRPIGRG AYGIVCSAVN SETTEEVAIK KIGNAFDNRI DAKRTLREIK LLRHMDHENV VAIRDIIRPP TRDEFNDVYI VYELMDTDLH QIIRSNQPLT EDHCQYFLYQ LLRGLKYIHS ANVLHRDLKP SNLLLNANCD LKICDFGLAR TTSETDFMTE YVVTRWYRAP ELLLNCNEYT AAIDVWSVGC IFMELLNREP LFPGRDYVQQ LKLITELIGS PEDSDLGFLK SENAKRYMQQ LMRYPKQPLG RKYPNMNPAA VDLIERMLVF DPYKRITVEQ ALSHPYLASL HDINDEPACH APFEFDFEQP SFTEEHIKEL IMMEALAFNP LPDMMQ |