Mp7g12670



Description

Annotation

Database ID Description
SUPERFAMILY SSF57850 RING/U-box
Coils Coil Coil
Pfam PF13923 Zinc finger, C3HC4 type (RING finger)
MobiDBLite mobidb-lite consensus disorder prediction
Gene3D G3DSA:3.30.40.10 Zinc/RING finger domain, C3HC4 (zinc finger)
Gene3D G3DSA:3.10.20.90 -
ProSitePatterns PS00518 Zinc finger RING-type signature.
PANTHER PTHR46293 E3 UBIQUITIN PROTEIN LIGASE DRIP1
ProSiteProfiles PS50089 Zinc finger RING-type profile.
SMART SM00184 ring_2
CDD cd16525 RING-HC_PCGF
KEGG K16277 E3 ubiquitin-protein ligase DRIP [EC:2.3.2.27]
KOG KOG2660 Locus-specific chromosome binding proteins; C-term missing; [S]
MapolyID Mapoly0003s0275 -
GO GO:0004842 ubiquitin-protein transferase activity

Nomenclature

Gene symbol Product Transcript ID Status
MpBMI1 Chromatin related protein Provisional

Associated Literature (AI-based literature mining, Beta-version)

Core PRC1 RING-finger E3 ligase (Mp7g12670) identified by BLAST; CRISPR knockout combined with Mpbmi1l caused strongly reduced growth and gemma-cup defects, global H2Aub loss by western blot, and altered H2Aub/H3K27me3 by ChIP-seq, showing it deposits H2Aub for Polycomb gene repression.

1 core 0 peripheral

Liu, S., et al. (2021b) · Genome Biology  research experimental subject
Core PRC1 RING-finger E3 ligase (Mp7g12670) identified by BLAST; CRISPR knockout combined with Mpbmi1l caused strongly reduced growth and gemma-cup defects, global H2Aub loss by western blot, and altered H2Aub/H3K27me3 by ChIP-seq, showing it deposits H2Aub for Polycomb gene repression.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp7g12670.1 chr7:15883691..15889320 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.