Mp2g24850



Description

Annotation

Database ID Description
Gene3D G3DSA:3.30.470.20 -
ProSiteProfiles PS50975 ATP-grasp fold profile.
PANTHER PTHR14217 INOSITOL-TETRAKISPHOSPHATE 1-KINASE
FunFam G3DSA:3.30.470.20:FF:000056 Inositol-tetrakisphosphate 1-kinase
Pfam PF17927 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain
Pfam PF05770 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like
PIRSF PIRSF038186 ITPK
KEGG K00913 inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]
MapolyID Mapoly0181s0012 -
GO GO:0000287 magnesium ion binding
GO GO:0032957 inositol trisphosphate metabolic process
GO GO:0046872 metal ion binding
GO GO:0005524 ATP binding
GO GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity
GO GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity
GO GO:0052746 obsolete inositol phosphorylation
GO GO:0005737 cytoplasm
GO GO:0047325 inositol-3,4,5,6-tetrakisphosphate 1-kinase activity

Nomenclature

Gene symbol Product Transcript ID Status
MpITPK1 inositol phosphate kinase Published

Associated Literature (AI-based literature mining, Beta-version)

Overexpression in Marchantia raised 5-InsP7 and InsP8 and weakened the Pi-starvation response (fewer/shorter rhizoids, lower PSI gene expression); MpITPK1 also complemented the Arabidopsis atitpk1-2 mutant. Identified as a kinase controlling Pi-responsive PP-InsP signaling.

2 core 2 peripheral

Pullagurla, N. J., et al. (2025) · Plant Physiology  research experimental subject
ITPK1-type inositol phosphate kinase (Mp2g24850); orchestrates phosphate homeostasis in M. polymorpha, producing inositol pyrophosphates that regulate the PSI response.
Chen, J., et al. (2024) · Plant Physiology  research experimental subject
Overexpression in Marchantia raised 5-InsP7 and InsP8 and weakened the Pi-starvation response (fewer/shorter rhizoids, lower PSI gene expression); MpITPK1 also complemented the Arabidopsis atitpk1-2 mutant. Identified as a kinase controlling Pi-responsive PP-InsP signaling.
Ghosh R, Yadav R, Pullagurla NJ, Rana P, Laha D. (2025) · FEBS letters  review citation background
Reviewed: overexpression of MpITPK1 elevates 5-InsP7 and an InsP8 isomer in M. polymorpha inositol phosphate metabolism.
Laurent, F., et al. (2025) · PLoS Genetics  research sequence background
A PP-InsP biosynthetic enzyme whose transcript was quantified by RNA-seq; no loss-of-function mutant generated.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp2g24850.1 chr2:30302560..30306270 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.