Mp5g17740



Description

Annotation

Database ID Description
PANTHER PTHR45747 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)
ProSiteProfiles PS51633 CXC domain profile.
CDD cd10519 SET_EZH
SMART SM01114 CXC_2
Pfam PF18264 CXC domain
Gene3D G3DSA:2.170.270.10 SET domain
Coils Coil Coil
FunFam G3DSA:2.170.270.10:FF:000001 Putative histone-lysine N-methyltransferase EZH2
SMART SM00317 set_7
ProSiteProfiles PS50280 SET domain profile.
SUPERFAMILY SSF82199 SET domain
Pfam PF00856 SET domain
KOG KOG1079 Transcriptional repressor EZH1; N-term missing; [K]
MapolyID Mapoly0084s0024 -
GO GO:0005634 nucleus
GO GO:0006338 chromatin remodeling
GO GO:0005515 protein binding
GO GO:0031507 heterochromatin formation
GO GO:0042054 histone methyltransferase activity
GO GO:0046976 histone H3K27 methyltransferase activity
GO GO:0003682 chromatin binding

Nomenclature

Gene symbol Product Transcript ID Status
MpE(z)2 E(z)2 Published

Associated Literature (AI-based literature mining, Beta-version)

PRC2 catalytic subunit; CRISPR/Cas9 dual knockout with MpE(z)3 in females, profiled by transcriptome and CUT&RUN. Maternal inheritance is essential for paternal H3K27me3 deposition. Loss reduces H3K27me3, reactivates paternal genes, drops embryo survival to ~20% and abolishes viable spores.

1 core 0 peripheral

Montgomery, S. A., et al. (2022) · eLife  research experimental subject
PRC2 catalytic subunit; CRISPR/Cas9 dual knockout with MpE(z)3 in females, profiled by transcriptome and CUT&RUN. Maternal inheritance is essential for paternal H3K27me3 deposition. Loss reduces H3K27me3, reactivates paternal genes, drops embryo survival to ~20% and abolishes viable spores.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp5g17740.1 chr5:21943434..21950554 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp5g17740.2 chr5:21943434..21950554 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.