Nagaoka, N., et al. · 2017 · Scientific Reports research
doi:10.1038/s41598-017-04886-0 PMID:28676660 PMC5496855
| Gene ID | Name | Evidence / Role | Function (this paper) |
|---|---|---|---|
| Mp2g24350 | MpDRP3 missing | experimental subject | Single-copy dynamin-related protein homologue studied by RT-PCR (two splice variants MpDRP3s/l), Citrine-fusion localization to mitochondrial constriction sites, and knockout (Mpdrp3). Mpdrp3 mutants showed severe growth retardation and blocked mitochondrial fission with elongated mitochondria, identifying MpDRP3 as required for mitochondrial fission. |
| Mp6g18400 | MpELM1 missing | experimental subject | Single-copy ELM1 homologue studied by transient-expression localization (MpELM1-Citrine surrounding mitochondria) and knockout (Mpelm1). Mpelm1 showed growth retardation and elongated mitochondria resembling Mpdrp3, with complementation restoring morphology, identifying MpELM1 as required for mitochondrial fission. |
| Mp5g02260 | MpFIS1 missing | experimental subject | Single-copy FIS1 homologue knocked out (Mpfis1); Citrine-MpFIS1 localized to mitochondrial surface and peroxisome-like bodies but Mpfis1 had no growth/developmental defects, indicating MpFIS1 has no major role in mitochondrial fission. |