Mp2g24350



Description

Annotation

Database ID Description
PANTHER PTHR11566 DYNAMIN
MobiDBLite mobidb-lite consensus disorder prediction
ProSiteProfiles PS51388 GED domain profile.
ProSitePatterns PS00410 Dynamin-type guanine nucleotide-binding (G) domain signature.
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
PRINTS PR00195 Dynamin signature
FunFam G3DSA:3.40.50.300:FF:001027 dynamin-related protein 3A
Pfam PF00350 Dynamin family
ProSiteProfiles PS51718 Dynamin-type guanine nucleotide-binding (G) domain profile.
Pfam PF02212 Dynamin GTPase effector domain
Gene3D G3DSA:3.40.50.300 -
SMART SM00053 dynamin_3
FunFam G3DSA:1.20.120.1240:FF:000018 Dynamin-related protein 3A
Gene3D G3DSA:1.20.120.1240 Dynamin, middle domain
SMART SM00302 GED_2
CDD cd08771 DLP_1
Pfam PF01031 Dynamin central region
Coils Coil Coil
KEGG K17065 dynamin 1-like protein [EC:3.6.5.5]
KOG KOG0446 Vacuolar sorting protein VPS1, dynamin, and related proteins; [UR]
MapolyID Mapoly0069s0084 -
GO GO:0003924 GTPase activity
GO GO:0005525 GTP binding
GO GO:0005874 microtubule
GO GO:0008017 microtubule binding
GO GO:0005737 cytoplasm
GO GO:0016020 membrane

Nomenclature

No gene symbols are registered for this gene.

Associated Literature (AI-based literature mining, Beta-version)

Single-copy dynamin-related protein homologue studied by RT-PCR (two splice variants MpDRP3s/l), Citrine-fusion localization to mitochondrial constriction sites, and knockout (Mpdrp3). Mpdrp3 mutants showed severe growth retardation and blocked mitochondrial fission with elongated mitochondria, identifying MpDRP3 as required for mitochondrial fission.

1 core 1 peripheral

Nagaoka, N., et al. (2017) · Scientific Reports  research experimental subject
Single-copy dynamin-related protein homologue studied by RT-PCR (two splice variants MpDRP3s/l), Citrine-fusion localization to mitochondrial constriction sites, and knockout (Mpdrp3). Mpdrp3 mutants showed severe growth retardation and blocked mitochondrial fission with elongated mitochondria, identifying MpDRP3 as required for mitochondrial fission.
Norizuk, T., et al. (2022) · Autophagy  research experimental tool
A mitochondrial dynamin-related protein; its dominant-negative form was expressed to inhibit mitochondrial fission, yielding spermatozoids with a single mitochondrion. Used as a genetic tool to probe mitochondrial fission's role in organelle reorganization.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp2g24350.1 chr2:29376614..29387139 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp2g24350.2 chr2:29376574..29387224 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp2g24350.3 chr2:29376574..29387224 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp2g24350.4 chr2:29376614..29387114 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.