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A small molecule antagonizes jasmonic acid perception and auxin responses in vascular and nonvascular plants.

Chini, A., et al. · 2021 · Plant Physiology   research

doi:10.1093/plphys/kiab369   PMID:34618088   PMC8566257

Linked genes (7)  3 core 4 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp2g00930 MpBHLH4 experimental subject bHLH14 transcription factor, OPDA-inducible marker; qPCR shows OPDA induction blocked by J4, evidencing J4 antagonism in Marchantia.
Mp2g26590 MpCOI1 experimental subject F-box jasmonate co-receptor of M. polymorpha, expressed/purified in insect cells with MpASK1. dn-OPDA induces its interaction with MpJAZ in pull-down assays, and the antagonist J4 directly blocks this Mp receptor complex, showing conserved JA perception.
Mp6g06230 MpJAZ experimental subject JAZ-domain repressor of M. polymorpha produced as recombinant MBP-MpJAZ; dn-OPDA induces MpCOI1-MpJAZ interaction in vitro, which J4 antagonizes.
Mp5g16920 MpDIR33 experimental comparator Dirigent-like OPDA-responsive marker gene; induced by 10 uM OPDA in Tak-1 plants, induction suppressed by J4 pretreatment.
Mp5g21220 MpPAT experimental comparator OPDA-responsive marker gene assayed by qPCR alongside MpDIR/MpBHLH4; J4 dampens its OPDA induction.
MpACT missing experimental tool Actin gene used as housekeeping reference for qRT-PCR normalization.
MpASK1 missing experimental tool SKP1-like adapter co-expressed and purified with MpCOI1 in insect cells to reconstitute the functional Mp receptor complex for pull-down assays.