MarpolBase - Phosphatidic acid phosphohydrolase modulates glycerolipid synthesis in Marchantia polymorpha and is crucial for growth under both nutrient-replete and -deficient conditions.

Phosphatidic acid phosphohydrolase modulates glycerolipid synthesis in Marchantia polymorpha and is crucial for growth under both nutrient-replete and -deficient conditions.

Shimojo, M., et al. · 2023 · Planta research

Gene ID	Name	Evidence / Role	Function (this paper)
Mp3g21770	MpPAH	experimental subject	Phosphatidic acid phosphohydrolase converting PA to DAG; two CRISPR/Cas9 knockouts (Mppah-1, Mppah-2) were generated and characterized. Mutants showed shorter rhizoids and reduced fresh weight, showing MpPAH modulates plastid glycolipid synthesis via the ER pathway. Unlike Arabidopsis PAH, it is essential for growth even under nutrient-replete conditions.
Mp3g25140	MpAPT	experimental tool	Adenine phosphoribosyltransferase (Mp3g25140) used as the stable reference gene for qPCR normalization.
Mp2g11200	MpBTA1 missing	experimental background	Betaine lipid (DGTS) transferase; qPCR showed expression induced by Pi starvation, consistent with increased DGTS.
Mp5g12930	MpDGD missing	experimental background	DGDG synthase; qPCR showed expression unchanged during Pi starvation, implying DGDG accumulates via a different mechanism.
Mp2g10950	MpMGDG	experimental background	MGDG synthase; qPCR showed expression rather suppressed under -Pi, unlike Arabidopsis type B MGDG synthases.
Mp5g24070	MpSQD	experimental background	SQDG synthase; qPCR showed induced expression under Pi and N starvation, correlating with SQDG accumulation.
Mp2g10160	MpSQD2 missing	experimental background	SQDG synthase; qPCR showed induced expression under Pi and N starvation, correlating with SQDG accumulation.