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MpmiR319 promotes gemma/gemma cup formation in the liverwort Marchantia polymorpha.

Futagami K, Tsuzuki M, Yoshida M, Watanabe Y. · 2025 · Journal of experimental botany   research

doi:10.1093/jxb/eraf148   PMID:40200901   PMC12369473

Linked genes (6)  5 core 1 peripheral

Gene ID Name Evidence / Role Function (this paper)
MpmiR319 missing experimental subject The mature miRNA encoded by the two MIR319 loci. The paper shows MpmiR319 promotes gemma/gemma cup formation by targeting and suppressing MpRKD and MpR2R3-MYB21 transcripts; loss of miR319 reduced gemma cup number.
Mp3g08965 MpMIR319A missing experimental subject One of the two M. polymorpha MIR319 loci producing the mature miR319. CRISPR knockout of MpMIR319A (with MpMIR319B) reduced gemma cup formation, demonstrating its role in promoting gemma/gemma cup development.
Mp4g01845 MpMIR319B missing experimental subject The second M. polymorpha MIR319 locus producing the same mature miR319; mir319b alleles (e.g. mir319bge-4) showed severe inhibition of gemma cup formation, supporting a role in promoting gemma/gemma cup development.
Mp3g05910 MpR2R3-MYB21 experimental subject GAMYB-family R2R3-MYB transcription factor identified as a second MpmiR319 target; miR319-resistant MpR2R3-MYB21 did not yield the gemma-cup-less phenotype, indicating it is less crucial than MpRKD for gemma cup formation.
Mp3g04030 MpRKD experimental subject RWP-RK domain-containing transcription factor identified as a target of MpmiR319, expressed in the rim and bottom of gemma cups. Expression of a miR319-resistant MpRKD produced gemma/gemma cup-less plants, indicating its repression by miR319 is critical for proper gemma cup formation.
MpKAI2 missing citation background Cited as one of the known pathways mediating gemma cup formation in M. polymorpha.