Rana P, Edathil Kadangodan A, Koley P, Ghosh R, Pullagurla NJ, Naik HC, Mondal P, Gayen S, Laha D. · 2025 · Nature chemical biology research
doi:10.1038/s41589-025-01961-w PMID:40745478
| Gene ID | Name | Evidence / Role | Function (this paper) |
|---|---|---|---|
| Mp5g20660 | MpGRAS6 | experimental subject | DELLA growth repressor; MpVIH-derived InsP8 binds MpDELLA, promoting its polyubiquitination and proteasomal degradation, revealing GA-independent DELLA regulation by inositol pyrophosphate. A binding-site mutant (MpDELLA-K294A/R295A) abolishes InsP8 binding. |
| Mp8g06840 | MpVIH | experimental subject | Diphosphoinositol-pentakisphosphate kinase responsible for synthesizing the inositol pyrophosphate messenger InsP8; MpVIH-derived InsP8 controls MpDELLA stability (validated by MpVIH-KD constructs, BiFC and docking). |
| — | MpBES1 missing | citation background | Cited as a BES1/BZR1-family transcription factor that regulates cell division and differentiation in M. polymorpha. |