Mp8g06840



Description

Annotation

Database ID Description
MobiDBLite mobidb-lite consensus disorder prediction
ProSiteProfiles PS50975 ATP-grasp fold profile.
FunFam G3DSA:3.40.50.11950:FF:000002 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
Pfam PF18086 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
Gene3D G3DSA:3.40.50.1240 -
Gene3D G3DSA:3.30.470.20 -
CDD cd07061 HP_HAP_like
ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature.
Pfam PF00328 Histidine phosphatase superfamily (branch 2)
SUPERFAMILY SSF53254 Phosphoglycerate mutase-like
PANTHER PTHR12750 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE
FunFam G3DSA:3.30.470.20:FF:000019 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
Gene3D G3DSA:3.40.50.11950 -
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like
KEGG K13024 inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24]
KOG KOG1057 Arp2/3 complex-interacting protein VIP1/Asp1, involved in regulation of actin cytoskeleton; [Z]
MapolyID Mapoly0013s0108 -
GO GO:0033857 5-diphosphoinositol pentakisphosphate 1-kinase activity
GO GO:0000829 diphosphoinositol pentakisphosphate kinase activity
GO GO:0046872 metal ion binding
GO GO:0006020 inositol metabolic process
GO GO:0005524 ATP binding
GO GO:0032958 inositol phosphate biosynthetic process
GO GO:0000828 inositol hexakisphosphate kinase activity

Nomenclature

Gene symbol Product Transcript ID Status
MpVIH inositol phosphate kinase Published

Associated Literature (AI-based literature mining, Beta-version)

Single PPIP5K gene encoding a bifunctional kinase/phosphatase. Mutants resemble Mppfa-dsp1 with vertical growth, reduced thallus, more rhizoids, fewer gemma cups, lower 1,5-InsP8 and higher 5-InsP7; the Mppfa-dsp1 Mpvip1 double mutant is severely stunted with high nitrate.

2 core 2 peripheral

Laurent, F., et al. (2025) · PLoS Genetics  research experimental subject
Single PPIP5K gene encoding a bifunctional kinase/phosphatase. Mutants resemble Mppfa-dsp1 with vertical growth, reduced thallus, more rhizoids, fewer gemma cups, lower 1,5-InsP8 and higher 5-InsP7; the Mppfa-dsp1 Mpvip1 double mutant is severely stunted with high nitrate.
Rana P, Edathil Kadangodan A, Koley P, Ghosh R, Pullagurla NJ, Naik HC, Mondal P, Gayen S, Laha D. (2025) · Nature chemical biology  research experimental subject
Diphosphoinositol-pentakisphosphate kinase responsible for synthesizing the inositol pyrophosphate messenger InsP8; MpVIH-derived InsP8 controls MpDELLA stability (validated by MpVIH-KD constructs, BiFC and docking).
Ghosh R, Yadav R, Pullagurla NJ, Rana P, Laha D. (2025) · FEBS letters  review citation background
Reviewed: MpVIH-derived inositol pyrophosphate InsP8 binds the growth repressor DELLA in M. polymorpha.
Pullagurla, N. J., et al. (2025) · Plant Physiology  research experimental comparator
VIH diphosphoinositol pentakisphosphate kinase; InsP pathway.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp8g06840.1 chr8:9245828..9262055 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.