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Chromatin state architecture governs transcription factor accessibility across plant genomes.

Shukla V, Axelsson E, Hisanaga T, Haseloff J, Berger F, Romani F. · 2026 · PLoS genetics   research

doi:10.1371/journal.pgen.1012015   PMID:41570051   PMC12867329

Linked genes (2)  2 core 0 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp5g18040	MpE(z)1	experimental subject	MpE(z)1 (Enhancer of zeste homolog) is the catalytic PRC2 subunit; the Mpknox2 Mpe(z)1 double mutant with reduced PRC2 activity was analysed by ChIP, showing depletion of H3K27me3 at facultative-heterochromatin states while H2Aub was retained.
Mp7g05320	MpKNOX2	experimental subject	The Mpknox2 Mpe(z)1 double mutant, deficient in PRC2 activity, was used to profile histone modifications (H3K27me3, H2Aub, H3K4me3, H3K9me1, H3K27me1) across Marchantia chromatin states. Loss of PRC2 depleted H3K27me3 but did not affect H2Aub deposition, indicating MpKNOX2 contributes to PRC2-dependent H3K27me3 in facultative heterochromatin.