← Literature list

Diversification of functional requirements for proteolysis of auxin response factors.

de Roij M, Heijdra E, Lamers J, Nishihama R, Borst JW, Weijers D. · 2026 · Nature communications   research

doi:10.1038/s41467-026-70440-0   PMID:41826301   PMC13128892

Linked genes (6)  2 core 4 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp1g12750	MpARF1	experimental subject	Activating A-class auxin response factor. This study showed MpARF1 shares the conserved arginine-dependent degradation mechanism with MpARF2, but stabilizing MpARF1 had little effect on development or auxin response, so its proteolysis is functionally dispensable.
Mp4g11820	MpARF2	experimental subject	Repressive B-class auxin response factor and the core focus of the study. The authors found MpARF2 degradation occurs across all developmental stages and that its stabilization severely impairs development and auxin response throughout the Marchantia lifecycle, showing proteolysis is critically required for its function.
—	MpHSP missing	experimental tool	Heat-shock promoter used to drive the inducible Cre-GR recombinase in the floxed conditional expression system.
—	MpUBE2 missing	experimental tool	Used as a constitutive promoter (proMpUBE2) to drive transgene expression.
Mp1g07070	MpARF3	experimental background	C-class auxin response factor; mentioned as one of the three single-copy ARF families in Marchantia, not functionally studied here.
Mp6g05000	MpIAA	experimental background	Aux/IAA gene examined in RNA-seq; found not differentially expressed when assessing transcriptional feedback regulation.