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Quantitative imaging reveals the role of MpARF proteasomal degradation during gemma germination.

Das, S., et al. · 2024 · Plant Communications   research

doi:10.1016/j.xplc.2024.101039   PMID:38988072   PMC11589480

Linked genes (9)  6 core 3 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp1g12750 MpARF1 experimental subject Class A activator ARF; MpARF1-mScarlet-I showed the highest accumulation among NAP components across most cell types during gemma germination. Its protein levels progressively declined and it was shown to be proteasomally degraded, tuning ARF stoichiometry for auxin-responsive gene activation.
Mp4g11820 MpARF2 experimental subject Repressor-class ARF; MpARF2-mScarlet-I accumulated weakly and was absent distal to the apical notch. Like MpARF1, it is proteasomally degraded and its levels decline during germination, contributing to regulated ARF stoichiometry.
Mp1g07070 MpARF3 experimental subject Class C ARF; MpARF3-mScarlet-I displayed a weak but broad accumulation in all cell types. Unlike MpARF1/MpARF2, it was unaffected by proteasome-inhibitor treatment and its pattern did not change, serving as a non-degraded contrast.
Mp6g05000 MpIAA experimental subject Sole canonical Aux/IAA repressor; undetectable in dormant gemma, MpIAA-mScarlet-I underwent rapid auxin-triggered degradation imaged in vivo, with a measured half-life of ~6.5 min, reporting on TIR1-mediated auxin signaling dynamics.
Mp2g02890 MpncARF experimental subject Non-canonical ARF lacking the DNA-binding domain; MpncARF-mScarlet-I showed low nuclear accumulation and positively influences auxin response in this system.
Mp6g02750 MpTIR1 experimental subject Sole TIR1 auxin receptor; MpTIR1-mScarlet-I showed low nuclear accumulation, was detectable at all stages with a gradual increase, and was shown active throughout gemma development in mediating IAA-triggered MpIAA degradation.
Mp3g23400 MpEF1 experimental tool Housekeeping gene used as a reference for transcript-level normalization.
Mp4g07110 MpSAND missing experimental tool Housekeeping gene used as a reference for transcript-level normalization.
Mp8g07850 MpncIAA citation background Non-canonical Aux/IAA mentioned in passing as a component of the minimal Marchantia auxin module.