Mp5g12010



Description

Annotation

Database ID Description
Gene3D G3DSA:2.130.10.10 -
MobiDBLite mobidb-lite consensus disorder prediction
ProSiteProfiles PS50294 Trp-Asp (WD) repeats circular profile.
PRINTS PR00320 G protein beta WD-40 repeat signature
ProSitePatterns PS00518 Zinc finger RING-type signature.
SMART SM00504 Ubox_2
SMART SM00184 ring_2
Gene3D G3DSA:3.30.40.10 Zinc/RING finger domain, C3HC4 (zinc finger)
ProSiteProfiles PS50089 Zinc finger RING-type profile.
SUPERFAMILY SSF57850 RING/U-box
SUPERFAMILY SSF50978 WD40 repeat-like
ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile.
FunFam G3DSA:2.130.10.10:FF:000090 E3 ubiquitin-protein ligase RFWD2 isoform X1
PANTHER PTHR44080 E3 UBIQUITIN-PROTEIN LIGASE COP1
ProSitePatterns PS00678 Trp-Asp (WD) repeats signature.
CDD cd16504 RING-HC_COP1
SMART SM00320 WD40_4
Coils Coil Coil
Pfam PF00400 WD domain, G-beta repeat
Pfam PF13923 Zinc finger, C3HC4 type (RING finger)
KEGG K10143 E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
KOG KOG0277 Peroxisomal targeting signal type 2 receptor; N-term missing; [U]
KOG KOG0297 TNF receptor-associated factor; C-term missing; [T]
MapolyID Mapoly0143s0030 -
GO GO:0016567 protein ubiquitination
GO GO:0005515 protein binding
GO GO:0061630 ubiquitin protein ligase activity
GO GO:0004842 ubiquitin-protein transferase activity
GO GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Nomenclature

Gene symbol Product Transcript ID Status
MpCOP1 A RING finger E3 ubiquitin ligase Published

Associated Literature (AI-based literature mining, Beta-version)

E3 ubiquitin ligase with RING-finger, coiled-coil, and WD40 domains; interacts with full-length MpSPA. It ubiquitinates MpHY5, a reaction promoted by MpSPA; CRISPR knockout lines were lethal, limiting full characterization.

2 core 3 peripheral

Liang Y, Podolec R, Chappuis R, Defossez E, Glauser G, Rötzer J, Stolze SC, Dolan L, Nakagami H, Demarsy E, Ulm R. (2026) · Plant Physiology  research experimental subject
E3 ubiquitin ligase; Mpcop1 mutants show a strong constitutive photomorphogenesis phenotype. COP1 function is much more independent of SPA in Marchantia than in Arabidopsis, and MpHY5 functions antagonistically to MpCOP1.
Zhang, L., et al. (2022b) · International Journal of Molecular Sciences  research experimental subject
E3 ubiquitin ligase with RING-finger, coiled-coil, and WD40 domains; interacts with full-length MpSPA. It ubiquitinates MpHY5, a reaction promoted by MpSPA; CRISPR knockout lines were lethal, limiting full characterization.
Lim, C. J., et al. (2024) · New Phytologist  research citation background
RING-type E3 ligase (Mp5g12010) cited and excluded from the PUB protein classification.
Roetzer J, Asper B, Meir Z, Edelbacher N, Merai Z, Datta S, Dolan L. (2026) · Current biology : CB  research experimental background
CONSTITUTIVELY PHOTOMORPHOGENIC 1; light-responsive gene in the induced set.
Clayton, W. A., et al. (2018) · Plant Journal  research experimental background
UVB-induced COP1 transcript in NanoString panel (annotation).

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp5g12010.1 chr5:15824597..15830825 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp5g12010.2 chr5:15824408..15830841 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.