Database	ID	Description
Gene3D	G3DSA:1.10.630.10	Cytochrome P450
PANTHER	PTHR47948	TRANS-CINNAMATE 4-MONOOXYGENASE
PRINTS	PR00385	P450 superfamily signature
FunFam	G3DSA:1.10.630.10:FF:000013	Trans-cinnamate 4-monooxygenase
ProSitePatterns	PS00086	Cytochrome P450 cysteine heme-iron ligand signature.
SUPERFAMILY	SSF48264	Cytochrome P450
Pfam	PF00067	Cytochrome P450
PRINTS	PR00463	E-class P450 group I signature
KEGG	K00487	trans-cinnamate 4-monooxygenase [EC:1.14.14.91]
KOG	KOG0156	Cytochrome P450 CYP2 subfamily; [Q]
MapolyID	Mapoly0163s0018	-
GO	GO:0005506	iron ion binding
GO	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO	GO:0004497	monooxygenase activity
GO	GO:0020037	heme binding

Gene symbol	Product	Transcript ID	Status
MpC4H1	Cytochrome P450, Secondary metabolism enzyme		Provisional

Primary, most highly expressed CYP73A paralog in M. polymorpha; encoded protein shows C4H activity in vitro. CRISPR mutants display dramatically reduced thallus area and fewer gemmae cups, with ~50% drop in two essential phenylpropanoid pathway intermediates.

2 core 4 peripheral

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