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Early evolution of the land plant circadian clock.

Linde, A.-M., et al. · 2017 · New Phytologist   research

doi:10.1111/nph.14487   PMID:28244104   PMC5638080

Linked genes (11)  8 core 3 peripheral

Gene ID Name Evidence / Role Function (this paper)
MpEFL missing experimental subject Single ELF4-like homologue that did not show rhythmic expression under any tested condition; not analyzed further by mutant or reporter assays.
Mp1g10870 MpELF3 experimental subject Single ELF3 homologue with evening-phased circadian expression; promoter:LUC shows rhythmic expression in neutral day and constant light, localized to meristematic regions.
Mp3g14360 MpFKF experimental subject Sole ZTL/FKF1-family member; did not show significant circadian rhythmicity. Interacts with MpGI in the photoperiodic pathway.
Mp1g13750 MpGI experimental subject Single GIGANTEA gene showing circadian rhythmicity; interacts with the sole ZTL-family member MpFKF and affects photoperiodic reproduction. Promoter:LUC rhythmic in meristematic regions.
Mp4g21220 MpLUX experimental subject Single LUX ARRHYTHMO homologue with evening-phased circadian expression; promoter:LUC shows bioluminescence rhythms under day/night and constant light, expressed in meristematic regions.
Mp2g16560 MpPRR experimental subject PRR-family gene clustering with the AtPRR3/7 clade; shows the strongest circadian transcriptional oscillation under day/night and constant light. Negatively regulated by MpTOC1 and positively by MpRVE; knockout disrupts bioluminescence patterning. Strongly expressed in meristematic and apical regions.
Mp2g14310 MpRVE experimental subject Single REVEILLE homologue clustering with the LCL clade; shows diel/circadian rhythmic expression in mature thalli. Knockout abolished 35S:LUC bioluminescence rhythm, and MpRVE positively regulates MpPRR. Promoter:LUC expression localized to meristematic and developing tissues.
Mp3g09460 MpTOC1 experimental subject Single TOC1 homologue clustering with the AtTOC1 clade; shows diel/circadian expression. Knockout abolished rhythmic bioluminescence under constant light, and MpTOC1 directly or indirectly represses MpPRR.
MpACT missing experimental tool Used as a reference/control gene for qRT-PCR expression normalization.
Mp3g23400 MpEF1 experimental tool ELONGATION FACTOR 1α used as a reference/control gene for qRT-PCR expression normalization.
Mp2g09390 MpTUB2 experimental tool MpβTubulin2 used as a reference/control gene for qRT-PCR expression normalization.