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SHOT GLASS, an R2R3-MYB transcription factor, promotes gemma cup and gametangiophore development in Marchantia polymorpha.

Sakai Y, Takami H, Yamaoka S, Kato H, Fukaki H, Kohchi T, Ishizaki K. · 2025 · The New phytologist   research

doi:10.1111/nph.70337   PMID:40734229   PMC12371152

Linked genes (21)  2 core 19 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp8g11870 MpSTG experimental subject Main subject of the paper; SHOT GLASS (MpSTG / MpR2R3-MYB5, Mp8g11870) is an R2R3-MYB transcription factor. Knockout (Mpstg ko/ge) plants failed to form normal gemma cups and showed impaired air chamber and gametangiophore development; complementation (gMpSTG-Citrine) rescued the phenotype and DEX-induced overexpression (MpSTG-GR) suppressed thallus growth, demonstrating MpSTG promotes gemma cup and gametangiophore development.
Mp6g16800 MpWRKY14 experimental subject In transcriptome analysis of the inducible MpSTG-GR line, MpWRKY14 was the most strongly upregulated gene after 2-h DEX treatment, identifying it as an early MpSTG-responsive target.
MpACT8 missing experimental tool Used as a qPCR internal reference control.
Mp6g11010 MpACTIN7 experimental tool Used as a qPCR internal reference control.
Mp3g23400 MpEF1 experimental tool Used as a qPCR internal reference control.
Mp2g09680 MpHA9 experimental tool Used as a proMpHA9:Citrine-GUS promoter reporter marking gemma cup floor cell identity to assess gemma cup development.
Mp3g17930 MpRSL1 experimental tool Used as a proMpRSL1:tdTomato-NLS promoter reporter marking developing gemmae.
Mp4g21300 Mp1R-MYB17 experimental background Downregulated DEG in MpSTG-induction transcriptome analysis.
Mp3g23300 MpBNB citation background Cited bHLH (BONOBO) transcription factor in reproductive development.
Mp5g10030 MpCYCB_1 experimental background Significantly downregulated upon MpSTG induction, consistent with reduced cell proliferation.
Mp4g08700 MpGARP2 experimental background Downregulated DEG in MpSTG-induction transcriptome analysis.
Mp6g04830 MpGCAM1 citation background Cited R2R3-MYB regulator of gemma cup initiation.
Mp5g20660 MpGRAS6 experimental background Upregulated DEG in MpSTG-induction transcriptome analysis; also noted as inhibiting gametangia formation via interaction with MpPIF.
Mp3g04970 MpKAN citation background Cited GARP transcription factor in gemma cup development context.
Mp1g00270 MpLOG citation background Cited cytokinin biosynthesis enzyme acting upstream of MpGCAM1.
MpMIR319 missing citation background Cited as source of MIR319-derived miRNAs.
Mp3g17350 MpPIF citation background Cited phytochrome-interacting factor in sexual reproduction regulation.
Mp3g04030 MpRKD citation background Cited RWP-RK domain transcription factor regulating gemma cup rim outgrowth.
Mp4g20600 MpRRB citation background Cited as a type-B response regulator that positively regulates MpGCAM1.
Mp2g25660 MpTRIHELIX12 experimental background Downregulated DEG in MpSTG-induction transcriptome analysis.
Mp1g24950 MpWRKY11 experimental background Upregulated DEG in MpSTG-induction transcriptome analysis.