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Functional analysis of the BEige and Chediak-Higashi domain gene MpSPIRRIG in Marchantia polymorpha.

Koebke, E., et al. · 2022 · Frontiers in Plant Science   research

doi:10.3389/fpls.2022.915268   PMID:36212282   PMC9537460

Linked genes (10)  2 core 8 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp2g15800 MpSPI missing experimental subject Alias/short form of the study's main gene; phylogenetically the closest homolog to AtSPI by BLAST.
Mp2g15880 MpSPIRRIG experimental subject Central subject of the study: a BEACH-domain gene characterized via a T-DNA mutant (Mpspi) in Marchantia polymorpha.
MpDCP1 missing experimental comparator Tested for interaction with MpSPI, but no interaction was found in pairwise yeast two-hybrid and BiFC assays.
Mp1g06880 MpLIP5 missing experimental comparator Tested as a co-localization and interaction partner of MpSPI PBW; yeast two-hybrid showed a strong interaction that could not be independently confirmed.
Mp8g01610 MpSKD1 missing experimental comparator Tested as a co-localization partner: MpSPI PBW co-localizes entirely with MpSKD1, but no yeast two-hybrid interaction was detectable.
Mp6g11010 MpACTIN7 citation tool Actin reference gene used for qPCR normalization; primers described previously.
MpAPT3 missing citation tool Reference gene used for RT-qPCR normalization; primers described previously.
Mp8g00450 MpARA6 experimental tool Endosomal marker (RABF1) used to test specificity; partial overlap with MpSPI supported direct MpLIP5/MpSKD1 interaction.
Mp8g16420 MpDCP2 missing experimental tool P-body marker co-expressed with MpSPI PBW, showing strong co-localization in punctate structures.
Mp1g08940 MpRAB5 experimental tool Endosomal marker used to test localization specificity; showed only partial overlap with MpSPI.