Database	ID	Description
CDD	cd00086	homeodomain
MobiDBLite	mobidb-lite	consensus disorder prediction
Coils	Coil	Coil
Gene3D	G3DSA:1.10.10.60	-
Pfam	PF02183	Homeobox associated leucine zipper
SMART	SM00389	HOX_1
FunFam	G3DSA:1.10.10.60:FF:000159	Homeobox-leucine zipper protein HAT5
ProSiteProfiles	PS50071	'Homeobox' domain profile.
ProSitePatterns	PS00027	'Homeobox' domain signature.
PRINTS	PR00031	Lambda-repressor HTH signature
Pfam	PF00046	Homeodomain
PANTHER	PTHR24326	HOMEOBOX-LEUCINE ZIPPER PROTEIN
SUPERFAMILY	SSF46689	Homeodomain-like
KEGG	K09338	homeobox-leucine zipper protein
KOG	KOG0483	Transcription factor HEX, contains HOX and HALZ domains; N-term missing; C-term missing; [K]
MapolyID	Mapoly0007s0221	-
GO	GO:0043565	sequence-specific DNA binding
GO	GO:0005634	nucleus
GO	GO:0003700	DNA-binding transcription factor activity
GO	GO:0003677	DNA binding
GO	GO:0006355	regulation of DNA-templated transcription
GO	GO:0045893	positive regulation of DNA-templated transcription
GO	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific

Gene symbol	Product	Transcript ID	Status
MpC1HDZ	transcription factor, HD, homeodomain protein		Published
MpHD3	transcription factor, HD, homeodomain protein		Published

MpC1HDZ is the sole Class I HD-Zip orthologue in M. polymorpha. Mpc1hdz loss-of-function mutants were more susceptible to Spodoptera frugiperda herbivory but more resistant to Phytophthora palmivora, and showed developmental defects (shortened gemma cups, reduced air pore density, absent surface papillae, loss of oil bodies), indicating a broad role for MpC1HDZ in epidermal cell differentiation and defense.

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